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Scientists have found that most patients with TMD also experience painful conditions in other parts of the body. These comorbid conditions include chronic fatigue syndrome, chronic headache, endometriosis, fibromyalgia, interstitial cystitis, irritable bowel syndrome, low back pain, sleep disorders, and vulvodynia. They are considered comorbid because they occur together more often than chance can explain. In addition, the conditions share other features. These findings are stimulating research into common mechanisms underlying all of these comorbid conditions. Indeed, other research indicates that TMD is a complex disease like hypertension or diabetes involving genetic,  environmental, behavioral, and sex-related factors. Note that many of the comorbidities mentioned are more prevalent or occur exclusively in women.


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